Investigation of T cell receptors in the peripheral blood of patients with active pulmonary tuberculosis.

نویسندگان

  • H H Akbulut
  • F Deveci
  • I Celik
  • F Ilhan
  • T Turgut
چکیده

T cells have the capability of recognizing target cells through their T cell receptors (TCRs). Thus, the percentages of CD3+/gamma-delta (gammadelta) TCR+ and CD3+/alpha-beta (alphabeta) TCR+ T lymphocytes were investigated in active and inactive pulmonary tuberculosis (PT) patients and in healthy individuals. CD3+ and CD3+/alphabeta TCR+ cell percentages were significantly lower in all PT patients than in healthy subjects. Percentages of CD3+/gammadelta and CD3+/alphabeta TCR+ were not statistically different between active and inactive PT patients. It was concluded that alphabeta TCR+ T cells might have a protective role in tuberculosis infection.

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عنوان ژورنال:
  • Indian journal of medical microbiology

دوره 27 1  شماره 

صفحات  -

تاریخ انتشار 2009